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Mesothelioma
Treatment
Articles
and Abstracts
Recent
geographic patterns of lung cancer and
mesothelioma mortality rates in 49
shipyard counties in the United States,
1970-94.
Am
J Ind Med 2000 May;37(5):512-21
Jemal
A, Grauman D, Devesa S
Division
of Cancer Epidemiology and Genetics,
National Cancer Institute, Bethesda,
Maryland, Maryland 20892-7244, USA.
BACKGROUND:
Lung cancer mortality rates among white
males in the United States were observed
to be elevated during 1950-69 in counties
with shipbuilding industries during World
War II; risk was found to be associated
with asbestos exposure. We evaluated the
geographic patterns in more recent years,
1970-94, for whites and compared them with
the 1950-69 patterns. METHODS: We
calculated age-adjusted rates and
estimated rate ratios between comparison
groups. RESULTS: Rates generally were
higher in shipyard counties than in all
nonshipyard counties and in coastal
nonshipyard counties for both sexes and
time periods. Rates increased markedly
from 1950-69 to 1970-94 in all groups,
with the changes more pronounced in
females than males. Pleural mesothelioma
mortality rates were also significantly
higher in shipyard counties than coastal
nonshipyard counties in all regions among
males but not among females. CONCLUSIONS:
The more pronounced changes in lung cancer
mortality rates among females in shipyard
counties may be attributed to the combined
effects of low asbestos exposures and
changes in smoking behavior. Am. J. Ind.
Med. 37:512-521, 2000. Published 2000
Wiley-Liss, Inc.
PMID:
10723045
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